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UNITED STATES
SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

SCHEDULE 13G

Under the Securities Exchange Act of 1934
(Amendment No. 1)*

XCYTE THERAPIES, INC.
(Name of Issuer)
Common Stock
(Title of Class of Securities)
98389F 10 1
(CUSIP Number)
December 31, 2005
(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

     o Rule 13d-1(b)

     o Rule 13d-1(c)

     þ Rule 13d-1(d)

* The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page.

The information required in the remainder of this cover page shall not be deemed to be “filed” for the purpose of Section 18 of the Securities Exchange Act of 1934 (“Act”) or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes).

Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number.

 
 

 

                     
CUSIP No.
  
98389F 10 1 

 

           
1   NAMES OF REPORTING PERSONS:
MPM BioVentures II, L.P.
   
  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY): 
   
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
  (a)   o
  (b)   þ
     
3   SEC USE ONLY:
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION:
   
  Delaware
       
  5   SOLE VOTING POWER:
     
NUMBER OF   0
       
SHARES 6   SHARED VOTING POWER:
BENEFICIALLY    
OWNED BY   0
       
EACH 7   SOLE DISPOSITIVE POWER:
REPORTING    
PERSON   0
       
WITH: 8   SHARED DISPOSITIVE POWER:
     
    0
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
   
  0
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):
   
  o
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
   
  0.0%
     
12   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):
   
  PN

2 of 12

 

                     
CUSIP No.
  
98389F 10 1 

 

           
1   NAMES OF REPORTING PERSONS:
MPM BioVentures II-QP, L.P.
   
  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY): 
   
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
  (a)   o
  (b)   þ
     
3   SEC USE ONLY:
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION:
   
  Delaware
       
  5   SOLE VOTING POWER:
     
NUMBER OF   0
       
SHARES 6   SHARED VOTING POWER:
BENEFICIALLY    
OWNED BY   0
       
EACH 7   SOLE DISPOSITIVE POWER:
REPORTING    
PERSON   0
       
WITH: 8   SHARED DISPOSITIVE POWER:
     
    0
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
   
  0
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):
   
  o
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
   
  0%
     
12   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):
   
  PN

3 of 12

 

                     
CUSIP No.
  
98389F 10 1 

 

           
1   NAMES OF REPORTING PERSONS:
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
   
  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY): 
   
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
  (a)   o
  (b)   þ
     
3   SEC USE ONLY:
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION:
   
  Germany
       
  5   SOLE VOTING POWER:
     
NUMBER OF   0
       
SHARES 6   SHARED VOTING POWER:
BENEFICIALLY    
OWNED BY   0
       
EACH 7   SOLE DISPOSITIVE POWER:
REPORTING    
PERSON   0
       
WITH: 8   SHARED DISPOSITIVE POWER:
     
    0
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
   
  0
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):
   
  o
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
   
  0%
     
12   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):
   
  PN

4 of 12

 

                     
CUSIP No.
  
98389F 10 1 

 

           
1   NAMES OF REPORTING PERSONS:
MPM Asset Management Investors 2000B LLC
   
  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY): 
   
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
  (a)   o
  (b)   þ
     
3   SEC USE ONLY:
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION:
   
  Delaware
       
  5   SOLE VOTING POWER:
     
NUMBER OF   0
       
SHARES 6   SHARED VOTING POWER:
BENEFICIALLY    
OWNED BY   0
       
EACH 7   SOLE DISPOSITIVE POWER:
REPORTING    
PERSON   0
       
WITH: 8   SHARED DISPOSITIVE POWER:
     
    0
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
   
  0
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):
   
  o
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
   
  0%
     
12   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):
   
  OO

5 of 12

 

                     
CUSIP No.
  
98389F 10 1 

 

           
1   NAMES OF REPORTING PERSONS:
Ansbert Gadicke
   
  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY): 
   
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
  (a)   o
  (b)   þ
     
3   SEC USE ONLY:
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION:
   
  United States
       
  5   SOLE VOTING POWER:
     
NUMBER OF   0
       
SHARES 6   SHARED VOTING POWER:
BENEFICIALLY    
OWNED BY   0
       
EACH 7   SOLE DISPOSITIVE POWER:
REPORTING    
PERSON  
       
WITH: 8   SHARED DISPOSITIVE POWER:
     
    0
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
   
  0
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):
   
  o
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
   
  0%
     
12   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):
   
  IN

6 of 12

 

                     
CUSIP No.
  
98389F 10 1 

 

           
1   NAMES OF REPORTING PERSONS:
Luke Evnin
   
  I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (ENTITIES ONLY): 
   
     
2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS):
  (a)   o
  (b)   þ
     
3   SEC USE ONLY:
   
   
     
4   CITIZENSHIP OR PLACE OF ORGANIZATION:
   
  United States
       
  5   SOLE VOTING POWER:
     
NUMBER OF   0
       
SHARES 6   SHARED VOTING POWER:
BENEFICIALLY    
OWNED BY   0
       
EACH 7   SOLE DISPOSITIVE POWER:
REPORTING    
PERSON   0
       
WITH: 8   SHARED DISPOSITIVE POWER:
     
    0
     
9   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON:
   
  0
     
10   CHECK IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES (SEE INSTRUCTIONS):
   
  o
     
11   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9):
   
  0%
     
12   TYPE OF REPORTING PERSON (SEE INSTRUCTIONS):
   
  IN

7 of 12

 

Item 1.
  (a)   Name of Issuer
Xcyte Therapies, Inc.
  (b)   Address of Issuer’s Principal Executive Offices
1124 Columbia Street, Suite 130
Seattle, WA 98104
Item 2.
  (a)   Name of Person Filing
MPM BioVentures II, LP
MPM BioVentures II-QP, L.P.
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
MPM Asset Management Investors 2000B LLC
Ansbert Gadicke
Luke Evnin
  (b)   Address of Principal Business Office or, if none, Residence
c/o MPM Capital L.P.
The John Hancock Tower
200 Clarendon Street, 54th Floor
Boston, MA 02116
  (c)   Citizenship
All entities were organized in Delaware, except MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG which was organized in Germany. All individuals are United States citizens.
  (d)   Title of Class of Securities
Common Stock
  (e)   CUSIP Number
98389F 10 1
Item 3.    If this statement is filed pursuant to §§240.13d-1(b), or 240.13d-2(b) or (c), check whether the person filing is a:
Not applicable
Item 4.    Ownership
  (a)   Amount Beneficially Owned:
         
MPM BioVentures II, LP
     0  
MPM BioVentures II-QP, L.P.
     0  
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
     0  
MPM Asset Management Investors 2000B LLC
     0  
Ansbert Gadicke
     0  
Luke Evnin
     0  

8 of 12

 

         
Percent of Class:
        
MPM BioVentures II, LP
     0  
MPM BioVentures II-QP, L.P.
     0  
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
     0  
MPM Asset Management Investors 2000B LLC
     0  
Ansbert Gadicke
     0  
Luke Evnin
     0  
  (b)   Number of shares as to which the person has:
  (i)   Sole power to vote or to direct the vote
         
MPM BioVentures II, LP
     0  
MPM BioVentures II-QP, L.P.
     0  
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
     0  
MPM Asset Management Investors 2000B LLC
     0  
Ansbert Gadicke
     0  
Luke Evnin
     0  
  (ii)   Shared power to vote or to direct the vote
         
MPM BioVentures II, LP
     0  
MPM BioVentures II-QP, L.P.
     0  
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
     0  
MPM Asset Management Investors 2000B LLC
     0  
Ansbert Gadicke
     0  
Luke Evnin
     0  
  (iii)   Sole power to dispose or to direct the disposition of
         
MPM BioVentures II, LP
     0  
MPM BioVentures II-QP, L.P.
     0  
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
     0  
MPM Asset Management Investors 2000B, LLC
     0  
Ansbert Gadicke
     0  
Luke Evnin
     0  
  (iv)   Shared power to dispose or to direct the disposition of
         
MPM BioVentures II, LP
     0  
MPM BioVentures II-QP, L.P.
     0  
MPM BioVentures GmbH & Co. Parallel-Beteiligungs KG
     0  
MPM Asset Management Investors 2000B LLC
     0  
Ansbert Gadicke
     0  
Luke Evnin
     0  

9 of 12

 

Item 5.    Ownership of Five Percent or Less of a Class
    If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following þ.
Item 6.    Ownership of More than Five Percent on Behalf of Another Person
Not Applicable
Item 7.    Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on By the Parent Holding Company or Control Person.
Not Applicable
Item 8.    Identification and Classification of Members of the Group
Not Applicable
Item 9.    Notice of Dissolution of a Group
Not Applicable
Item 10.    Certification
Not Applicable

10 of 12

 

SIGNATURE
     After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.
Dated: February 9, 2006
                 
MPM BIOVENTURES II, L.P.       MPM BIOVENTURES II-QP, L.P.
 
                
By:
  MPM Asset Management II, L.P., its General Partner       By:   MPM Asset Management II, L.P., its General Partner
 
                
By:
  MPM Asset Management II LLC,
its General Partner 		      By:   MPM Asset Management II LLC,
its General Partner
 
                
By:
          \s\ Luke Evnin       By:           \s\ Luke Evnin
 
               
 
  Name: Luke B. Evnin           Name: Luke B. Evnin
 
  Title: Manager           Title: Manager
 
                
 
                
MPM BIOVENTURES GMBH & CO.
PARALLEL-BETEILIGUNGS KG		       MPM ASSET MANAGEMENT INVESTORS
2000B LLC
 
                
By:
  MPM Asset Management II LP, in its       By:           \s\ Luke Evnin
capacity as the Special Limited Partner           Name: Luke B. Evnin
 
              Title: Manager
 
                
By:
  MPM Asset Management II LLC, its            
General Partner            
 
                
By:
          \s\ Luke Evnin            
 
               
 
  Name: Luke B. Evnin            
 
  Title: Manager            
 
                
 
                
By:
          \s\ Ansbert Gadicke       By:           \s\ Luke Evnin
 
               
 
  Name: Ansbert Gadicke           Name: Luke B. Evnin

11 of 12

 

EXHIBIT A
JOINT FILING AGREEMENT
     In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the undersigned agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Common Stock of Xcyte Therapies, Inc. and further agree that this agreement be included as an exhibit to such filing. Each party to the agreement expressly authorizes each other party to file on its behalf any and all amendments to such statement. Each party to this agreement agrees that this joint filing agreement may be signed in counterparts.
     In evidence whereof, the undersigned have caused this Agreement to be executed on their behalf this 9th day of February, 2006.
                 
MPM BIOVENTURES II, L.P.       MPM BIOVENTURES II-QP, L.P.
 
                
By:
  MPM Asset Management II, L.P., its General Partner       By:   MPM Asset Management II, L.P., its General Partner
 
                
By:
  MPM Asset Management II LLC,
its General Partner 		      By:   MPM Asset Management II LLC,
its General Partner
 
                
By:
          \s\ Luke Evnin       By:           \s\ Luke Evnin
 
               
 
  Name: Luke B. Evnin           Name: Luke B. Evnin
 
  Title: Manager           Title: Manager
 
                
 
                
MPM BIOVENTURES GMBH & CO.
PARALLEL-BETEILIGUNGS KG		       MPM ASSET MANAGEMENT INVESTORS
2000B LLC
 
                
By:
  MPM Asset Management II LP, in its       By:           \s\ Luke Evnin
capacity as the Special Limited Partner           Name: Luke B. Evnin
 
              Title: Manager
 
                
By:
  MPM Asset Management II LLC, its            
General Partner            
 
                
By:
          \s\ Luke Evnin            
 
               
 
  Name: Luke B. Evnin            
 
  Title: Manager            
 
                
 
                
By:
          \s\ Ansbert Gadicke       By:           \s\ Luke Evnin
 
               
 
  Name: Ansbert Gadicke           Name: Luke B. Evnin

12 of 12