UNITED STATES
                       SECURITIES AND EXCHANGE COMMISSION
                             Washington, D.C. 20549
                               -------------------

                                 SCHEDULE 13G/A

                    Under the Securities Exchange Act of 1934

                               (Amendment No. 1)*

                              Xcyte Therapies, Inc.
                                (Name of Issuer)

                    Common stock, par value $0.001 per share
                         (Title of Class of Securities)

                                    98389F309
                                 (CUSIP Number)

                                December 31, 2005
             (Date of Event Which Requires Filing of this Statement)


Check the appropriate box to designate the rule pursuant to which this Schedule
is filed:

[ ]   Rule 13d-1(b)
[X]   Rule 13d-1(c)
[ ]   Rule 13d-1(d)


- -----------------
         * The remainder of this cover page shall be filled out for a reporting
person's initial filing on this form with respect to the subject class of
securities, and for any subsequent amendment containing information which would
alter the disclosures provided in a prior cover page.

         The information required in the remainder of this cover page shall not
be deemed to be "filed" for purposes of Section 18 of the Securities Exchange
Act of 1934 ("Act") or otherwise subject to the liabilities of that section of
the Act but shall be subject to all other provisions of the Act (however, see
the Notes).

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge Capital Corporation - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands, British West Indies - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** 00 - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge International LLC - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands, British West Indies - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** OO-Limited Liability Company - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge Capital Management, LLC 20-1901985 - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION State of Delaware - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** OO-Limited Liability Company - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge Master L.P. - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands, British West Indies - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** PN-Partnership - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge Capital L.P. - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION State of Delaware - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** PN-Partnership - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge GP, Ltd. - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION Cayman Islands, British West Indies - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** OO-Limited Liability Company - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Highbridge GP, LLC - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION State of Delaware - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** OO-Limited Liability Company - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Glenn Dubin - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION United States - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** IN - -----------------------------------------------------------------------------

CUSIP No. 98389F309 - ------------------------------------------------------------------------------- (1) NAMES OF REPORTING PERSONS I.R.S. IDENTIFICATION NO. OF ABOVE PERSONS (ENTITIES ONLY) Henry Swieca - ------------------------------------------------------------------------------- (2) CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP ** (a) [X] (b) [ ] - ------------------------------------------------------------------------------- (3) SEC USE ONLY - ------------------------------------------------------------------------------- (4) CITIZENSHIP OR PLACE OF ORGANIZATION United States - ------------------------------------------------------------------------------- NUMBER OF (5) SOLE VOTING POWER -0- SHARES ---------------------------------------------------------------- (6) SHARED VOTING POWER BENEFICIALLY 187 shares of Common Stock. See Item 4(a). OWNED BY ---------------------------------------------------------------- EACH (7) SOLE DISPOSITIVE POWER -0- REPORTING ---------------------------------------------------------------- (8) SHARED DISPOSITIVE POWER 187 shares of Common Stock. PERSON WITH ---------------------------------------------------------------- (9) AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 187 shares of Common Stock. - ------------------------------------------------------------------------------- (10) CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ** [ ] - ------------------------------------------------------------------------------- (11) PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9) 0.0% (See Item 4(b)) - ------------------------------------------------------------------------------- (12) TYPE OF REPORTING PERSON ** IN - -----------------------------------------------------------------------------

This Amendment No. 1 (this "Amendment") amends the statement on Schedule 13G filed on November 8, 2004 (as amended, the "Schedule 13G") with respect to shares of common stock (the "Common Stock") of Xcyte Therapies, Inc., a Washington corporation (the "Company"). Capitalized terms used herein and not otherwise defined in this Amendment have the meanings set forth in the Schedule 13G. This Amendment amends and restates items 2 (a), 2(b), 2(c), 4 and 5 in their entirety as set forth below. Item 2(a). Name of Person Filing Item 2(b). Address of Principal Business Office Item 2(c). Citizenship Highbridge International LLC The Cayman Corporate Centre, 4th Floor 27 Hospital Road Grand Cayman, Cayman Islands, British West Indies Citizenship: Cayman Islands, British West Indies Highbridge Capital Corporation The Cayman Corporate Centre, 4th Floor 27 Hospital Road Grand Cayman, Cayman Islands, British West Indies Citizenship: Cayman Islands, British West Indies Highbridge Capital Management, LLC 9 West 57th Street, 27th Floor New York, New York 10019 Citizenship: State of Delaware Highbridge Master L.P. c/o Harmonic Fund Services Cayman Financial Centre Tower C 36 Dr. Roy's Drive George Town, Grand Cayman Cayman Islands, British West Indies Citizenship: Cayman Islands, British West Indies Highbridge Capital L.P. c/o Highbridge Capital Management, LLC 9 West 57th Street, 27th Floor New York, New York 10019 Citizenship: State of Delaware Highbridge GP, Ltd. c/o Harmonic Fund Services Cayman Financial Centre Tower C 36 Dr. Roy's Drive George Town, Grand Cayman Cayman Islands, British West Indies Citizenship: Cayman Islands, British West Indies Highbridge GP, LLC c/o Harmonic Fund Services Cayman Financial Centre Tower C 36 Dr. Roy's Drive

George Town, Grand Cayman Cayman Islands, British West Indies Citizenship: Cayman Islands, British West Indies Glenn Dubin c/o Highbridge Capital Management, LLC 9 West 57th Street, 27th Floor New York, New York 10019 Citizenship: United States Henry Swieca c/o Highbridge Capital Management, LLC 9 West 57th Street, 27th Floor New York, New York 10019 Citizenship: United States Item 4. Ownership (a) Amount beneficially owned As of the date of this Statement, each Reporting Person may be deemed the beneficial owner of 187 shares of Common Stock held by Highbridge International LLC. Highbridge International LLC is a subsidiary of Highbridge Master L.P. Highbridge Capital Corporation and Highbridge Capital L.P. are limited partners of Highbridge Master L.P. Highbridge GP, Ltd. is the General Partner of Highbridge Master L.P. Highbridge GP, LLC is the General Partner of Highbridge Capital L.P. Highbridge Capital Management, LLC is the trading manager of Highbridge Capital Corporation, Highbridge Capital L.P. and Highbridge Master L.P. Glenn Dubin is a Co-Chief Executive Officer of Highbridge Capital Management, LLC. Henry Swieca is a Co-Chief Executive Officer of Highbridge Capital Management, LLC. The foregoing should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of shares of Common Stock owned by another Reporting Person. In addition, each of Highbridge Master L.P., Highbridge Capital Corporation, Highbridge Capital L.P., Highbridge GP, Ltd., Highbridge GP, LLC, Highbridge Capital Management, LLC, Glenn Dubin and Henry Swieca disclaims beneficial ownership of shares of Common Stock owned by Highbridge International LLC. (b) Percent of class The Company's quarterly report that was filed on Form 10-Q that was filed on November 14, 2005, indicates there were 19,672,393 shares of Common Stock outstanding as of November 7, 2005. Therefore, based on the Company's outstanding shares of Common Stock issued by the Company, the Reporting Persons may be deemed to beneficially own approximately 0.0% of the outstanding shares of Common Stock of the Company. The foregoing should not be construed in and of itself as an admission by any Reporting Person as to beneficial ownership of shares of Common Stock owned by another Reporting Person. (c) Number of shares as to which such person has: (i) Sole power to vote or to direct the vote 0 (ii) Shared power to vote or to direct the vote 187 shares of Common Stock. (iii) Sole power to dispose or to direct the disposition of 0 (iv) Shared power to dispose or to direct the disposition of 187 shares of Common Stock. Item 5. Ownership of Five Percent or Less of a Class

If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following: [x]

SIGNATURE After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Dated February 13, 2006 HIGHBRIDGE INTERNATIONAL LLC HIGHBRIDGE CAPITAL CORPORATION By: /s/ Howard Feitelberg By: /s/ Howard Feitelberg ------------------------ --------------------------- Name: Howard Feitelberg Name: Howard Feitelberg Title: Director Title: Controller HIGHBRIDGE CAPITAL MANAGEMENT, LLC HIGHBRIDGE GP, LTD. By: /s/ Carolyn Rubin By: /s/ Clive Harris ------------------------ --------------------------- Name: Carolyn Rubin Name: Clive Harris Title: Deputy General Counsel Title: Director HIGHBRIDGE MASTER L.P. HIGHBRIDGE GP, LLC By: /s/ Clive Harris --------------------------- By: Highbridge GP, Ltd. Name: Clive Harris its General Partner Title: Director By: /s/ Clive Harris ------------------------ Name: Clive Harris Title: Director HIGHBRIDGE CAPITAL L.P. /s/ Henry Swieca By: Highbridge GP, LLC ---------------------------- its General Partner HENRY SWIECA By: /s/ Clive Harris ------------------------ Name: Clive Harris Title: Director /s/ Glenn Dubin - ---------------------------- GLENN DUBIN

EXHIBIT I JOINT FILING AGREEMENT This will confirm the agreement by and among the undersigned that the Schedule 13G filed with the Securities and Exchange Commission on or about the date hereof with respect to the beneficial ownership by the undersigned of the Common Stock of Xcyte Therapies, Inc., a Washington corporation, is being filed, and all amendments thereto will be filed, on behalf of each of the persons and entities named below in accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended. This Agreement may be executed in two or more counterparts, each of which shall be deemed an original, but all of which together shall constitute one and the same instrument. Dated as of February 13, 2006 HIGHBRIDGE INTERNATIONAL LLC HIGHBRIDGE CAPITAL CORPORATION By: /s/ Howard Feitelberg By: /s/ Howard Feitelberg ------------------------ --------------------------- Name: Howard Feitelberg Name: Howard Feitelberg Title: Director Title: Controller HIGHBRIDGE CAPITAL MANAGEMENT, LLC HIGHBRIDGE GP, LTD. By: /s/ Carolyn Rubin By: /s/ Clive Harris ------------------------ --------------------------- Name: Carolyn Rubin Name: Clive Harris Title: Deputy General Counsel Title: Director HIGHBRIDGE MASTER L.P. HIGHBRIDGE GP, LLC By: /s/ Clive Harris --------------------------- By: Highbridge GP, Ltd. Name: Clive Harris its General Partner Title: Director By: /s/ Clive Harris ------------------------ Name: Clive Harris Title: Director HIGHBRIDGE CAPITAL L.P. /s/ Henry Swieca By: Highbridge GP, LLC ---------------------------- its General Partner HENRY SWIECA By: /s/ Clive Harris ------------------------ Name: Clive Harris Title: Director

/s/ Glenn Dubin - ---------------------------- GLENN DUBIN